N-METHYLSACCHARIN(N-METHYLSACCHARIN) is a common artificial sweetener. Its chemical name is N-methyl -2-saccharin, chemical formula is C8H9NO3S, its molecular structure has a methyl substituted on the nitrogen atom of saccharin. The N-METHYLSACCHARIN is white crystal, taste sweet without aroma.
The primary use of N-METHYLSACCHARIN is as a sweetener for foods and beverages. It is sweeter than sucrose, but it has almost no calories and does not cause tooth decay. Therefore, it is often used to make low-calorie and sugar-free foods. N-METHYLSACCHARIN can also be used in the pharmaceutical industry as a pharmaceutical or cosmetic sweetener.
A common method of preparing N-METHYLSACCHARIN is through the methylation reaction of saccharin. This reaction transfers the methyl group in the methanol to the nitrogen atom of the saccharin. The preparation process requires a methylating agent, usually sodium formate and a sulfuric acid catalyst. The reaction is generally carried out at elevated temperature and purified by crystallization to give the pure product.
Regarding safety information, N-METHYLSACCHARIN has been approved by the FDA as a food additive and is considered safe in many countries. It has a strong sweet taste and requires less, but long-term consumption of excessive amounts may have negative health effects. Some studies suggest that large doses of N-METHYLSACCHARIN may be associated with the development of cancer. Therefore, it is recommended to follow appropriate dosage and frequency of consumption when using N-METHYLSACCHARIN, and to follow food safety guidelines. For pregnant women, children and people allergic to sweeteners, should try to avoid the use.